Interleukin-1 polymorphism and treatment response in HCV patients

This book represents the first study on the correlation between IL-1 (+3953 C/T) gene polymorphism and the response of INF-therapy in genotype 4 HCV infected patients. The results encourages us to further assess this single nucleotide polymorphism as a marker for prediction of response to therapy and disease progression which would have great implications in saving money, time and avoiding unnecessary adverse effects.