Vesiculobullous lesions of the Oral Cavity

Clinical identification of intact vesicle and bulla in the oral cavity is really a challenge, due to the regular irritation and the friable nature of oral mucosa. Rupture of these lesions leads to erosions or ulcerations on the surface, hence making the diagnosis of vesiculobullous lesions even more difficult, due to the fact that the differential diagnosis along with VB lesions will also include ulcerative, immunological-mediated diseases, neoplasms and systemic diseases. Hence, knowledge of the clinical presentation of these disorders and the relevant diagnostic procedures is important not just for dermatologists, but also for general practitioners and dentists.