Smad Signal Transduction

Smad Signal Transduction

AngličtinaPevná väzba
Springer-Verlag New York Inc.
EAN: 9781402045424
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Podrobné informácie

For the first time world-leading experts in the area of cellular signaling have joined to the production of a book on Smad signal transduction. Smads are the principal intracellular effectors of TGF-b family members that control numerous cellular responses with critical roles in development and in tissue homeostasis. In a series of 22 cutting-edge chapters forward looking reviews of Smads are provided that cover their discovery, evolution, role in development, mechanism of action and regulation, and how deregulation in Smad signalling contributes to human diseases. Written for an audience with basic understanding of molecular and cell biology, this volume provides an in-depth review of a rapidly developing field and extensive cross-references between chapters are provided. This book will be of particular interest to basic and applied biomedical researchers (students, post-docs or group leaders) with desire to understand the principles of cell-cell communication and mechanisms by which signaling pathways and gene programs control cell proliferation and differentiation, and how this knowledge may come to be applied in the clinic.

EAN 9781402045424
ISBN 1402045425
Typ produktu Pevná väzba
Vydavateľ Springer-Verlag New York Inc.
Dátum vydania 24. augusta 2006
Stránky 472
Jazyk English
Rozmery 235 x 155
Krajina United States
Čitatelia Professional & Scholarly
Ilustrácie XIV, 472 p.
Editori Dijke, Peter; Heldin Carl-Henrik
Séria Proteins and Cell Regulation